Rheumatology is a sub-specialty of medicine dealing with diagnosis and treatment of diseases predominantly affecting the joints and connective tissues. Various auto-immune disorders, affecting multiple organ systems also fall under its purview. The Department of Rheumatology at Manipal Hospitals, Bangalore is the pioneer in its field and is well known all over India. It provides diagnostic facilities and therapy for disorders like rheumatoid arthritis, ankylosing spondylitis, gout, and osteoarthritis. Critical auto-immune diseases like lupus, scleroderma & dermatomyositis are also dealt with here. Immuno-modulatory drugs are used for chronic and recurring problems. Other treatments include immunosuppressive therapy along with physical medicine and rehabilitation.